Both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. Key words: Leucas aspera, Antibacterial activity. Leucas aspera, Leucas zeylanica, antifungal, dermatophytes. RESULTS: Antifungal activity of Leucas sp. against Dermatophytes. Objective: The aim of this study was to explicate antibacterial, antifungal, and antioxidant activities of Leucas aspera flowers. Methods: Antibacterial activity was.

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In a previous study, 2 showed that the methanol extract of leaf of Leucas aspera did not restrain the growth of fungal strains Candida albicans and Aspergillus fumigatesbut in this case study it is apparent to facilitate that the methanol extract of both the selected plants of Lamiaceae family showed a in negligible inhibition activity against Candida albicans and other species of Aspergillus generaAspergillus flavus.

Leucas aspera – medicinal plant: The microorganisms chosen to be studied were Gram positive, S. Parekh J, Chanda S. The tubes were then examined after 12 h and the number of surviving larvae in each tube was counted.

The same procedure was performed on the other 3 plant parts which were root 2. Swati Paul, Dibyajyoti Saha. The activity may be due to their hydrophobic action which is responsible for the breakage of lipid bilayer of the cell membrane, leading to losing its permeability and a subsequent leakage of its cell contents Then, the segregated parts were cut into small size and sun dried for 1 week. This test was done in triplicates.

Brine shrimp lethality bioassay was carried out according to Meyer et al [16] to investigate the cytotoxicity of the root extract. The results of this study support the use of Leucas aspera and Leucas zeylanica in traditional Indian medicine and show that methanolic leaf extract of these plants can be used as an easily accessible source of natural antifungal agent and can be of assistance in some dermatological problems.


The preservative effect of many plant spices and herbs suggests the presence of antioxidative and antimicrobial constituents in their tissues. Vitaceae and Cyperus rotundus L. Phytochemicals analysis should be carried out antiicrobial characterize the compounds in L. Ahmed I, Beg A. The mode of antimicrobial action of the essential oil of Melaleucaalternifolia tea tree oil.

Extraction of Bioactive compound from plant material: The pf were filtered. Conclusions The present finding suggests that the methanol root extract of L.

The result obtained shows that all the extracts expressed remarkable antifungal activity with zone of inhibition ranging from 5 to 10mm.

User Username Password Remember me. The LC 50 was obtained again for this 24 h observation. A sterile swab was used to spread fungal culture evenly over the medium. Prior RL, Cao G.

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Diet and health implications. Several research works have been carried out to study about the phytochemical components of Leucas aspera and also about aapera antimicrobial activity of the plant extracts of Leucas aspera against five human pathogens.

Known antioxidants such as vitamin E and butylated hydroxytoluene BHT were used as positive controls. Pharmaceutical properties in vitro of various extracts of Mimosa pudica L.

The difference in the zone of inhibition is probably due to the different solvents used for extraction and also the fact that the extracts in the previous study were from the entire plant whereas in this study the plant parts were segregated and tested individually. The percentage of mortality was plotted against the logarithm of zctivity.

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It has been widely observed and accepted that the medicinal value of plants lies in the bioactive phytocomponents present in the plants Veermuthu et al. On the other hand, the scavenging activity of flower, leaf and stem extracts was The presence of alkaloids, steroids, tannins, flavonoids and glycosides were confirmed during preliminary phytochemical screening of this plant World Bank Technical Paper.


The antimixrobial screening of the both extracts were carried out by determining the zone of inhibition using disc diffusion method Mc Farland, against five bacteria. Res ; 2 4: Journal of American Medical Association, 49, A, Yousuf M, Chowdhury J. Separation of Leucas asperaa medicinal plant of Bangladesh, guided by prostaglandin inhibitory and antioxidant activities. The results showed that azpera extract exhibited the greatest free radical scavenging activity among the plant extracts with a mean percentage of Methanol extract of root possessed antioxidant activity near the range of vitamin E and thus could be a potential rich source of natural antioxidant.

Curr Med Chem ;8: Brine shrimp lethality bioassay of root extract Acttivity shrimp lethality bioassay was carried out according to Meyer et al [16] to investigate the cytotoxicity of atcivity root extract.

Antioxidant and antibacterial activity of different parts of Leucas aspera

Email this article Login required Email the author Login required. Screening methods for natural products with antimicrobial activity: Leucqs the present study the leaves and root extracts of Leucas aspera aspega investigated for invitro antibacterial activity and phytochemical analysis.

Asian Pac J Trop Biomed ;2: Leucas asperaAntioxidant activity, Antimicrobial activity, Cytotoxic activity, Inhibition of zone, Natural antioxidant, Labiatae. Free Radic Biol Med ; The root extract showed the highest mean zone of inhibition ranging from 9. In the previous investigation Gandhiraja et al.

J Plant Taxono ; Besides this, the chloroform and acetone extract showed good activity against the growth of Staphylococcus aureus 22mm ,Klebiella pneumonia 21mm ,Bacillus cereus 20mm and Enterobacter faecalis 15mm.

At a higher concentration, these extracts may exhibit more significant free radical scavenging activity. However, in this study, the plant extracts root, stem and flower were effective against both Gram positive and Gram negative bacteria.