Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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A Disease Activity Index score was used as a reliable tool to assess the extent of the gastrointestinal disease in the DSS-induced experimental colitis.

Intestinal anti-inflammatory activity of the Serpylli herba extract in experimental models of rodent colitis. Journal of Medicinal Food. The reduction of pathogens associated with systemic and oral infections, using natural products to adstrnigens the ability to form biofilms, could be an effective approach to prevent and control oral diseases.

Amphipterygium adstringens – Wikipedia

Trees and Shrubs of Mexico pt. The experiment was performed by duplicate in three independent tests. Long-chain phenols from the bark of Amphypterygium adstringens.

Biochemical and Biophysical Research Communications. Moreover, there has been a decline in research, development, and approvals of new antimicrobial agents. EGCG reduces experimental colon injury by inhibiting macrophage chemotaxis toward N-formyl-L-leucyl-L-phenylalanine, thereby suppressing the mast cells and macrophage activities [ 43 ].

In vitro antioxidant tests using free radical traps are relatively straightforward to perform.


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The findings of this study suggest that AaEE has substantial potential for the treatment of inflammatory colitis. Doxorubicin was used as positive control. AaEE showed a content of flavonoids of Experimental colitis models have been used to identify therapeutic agents and elucidate the underlying physiologic mechanisms of UC.

MIC was determined as the lowest concentration of CE that inhibited microorganism growth.

In Vitro Antimicrobial and Antiproliferative Activity of Amphipterygium adstringens

View at Google Scholar R. Treatments for these infections have grown to be a great challenge, because of a rise in the frequency of infections and an increasing resistance to standard antifungal therapy.

The mean of three readings was used to interpolate with the gallic acid curve 6. The untreated group received tap water without DSS. Epigallocatechingallate EGCGa catechin of the green tea plant Camellia sinensisshows strong expanding beneficial effects in studies of diabetes, Parkinson’s disease, Alzheimer’s disease, stroke, inflammation, obesity, and cancer [ 42 ]. Body weight loss and bloody stools were observed in mice acutely exposed to DSS.

The antioxidant activity values were determined according to the following equation: Adstringenw of complementary and alternative medicine use and its impact on medication adherence in inflammatory bowel disease. Total Phenolic Content The Folin-Ciocalteu method [ 22 ] was used to determine the total phenolic content of a 0.

The value of experimental models of colitis in predicting efficacy of biological therapies for inflammatory bowel diseases. Similarly, low TGI values for CE were proved in every tumor cell line included in the selected panel.


Its virulence relies on its ability to form biofilms on teeth surface, to degrade carbohydrates particularly refined sugars from food with the formation of large amounts of organic acids that demineralize tooth enamel, and to adapt and tolerate environmental stresses, particularly low pH aciduricity [ 29 ].

One of these mechanisms could be related to the well-known antioxidant properties ascribed to the majority of the plant extracts, due to their content in polyphenolic compounds, as it happens with the present extract that contains flavonoids, which has been reported to exert antioxidant properties [ 3839 ].

Introduction Ulcerative colitis UC is a major type of inflammatory bowel disease characterized by chronic, relapsing intestinal inflammation with extensive damage of colonic mucosa. This page was last edited on 18 Julyat Whole plant and bark of Amphipterygium adstringens growing in Michoacan, Mexico. Natural products, herbs, and dietary components have shown therapeutic effect against inflammatory colitis [ 37 ]. Rt min Name Type 3. For this reason, the development of new therapies that combine efficacy, convenient dosing, and fewer side effects is an important goal in human UC therapy.